Tehran University of Medical Sciences Journal of Pharmaceutical Care 2322-4630 9 2 2021 06 27 52 54 EN Zahra Karimian Department of Clinical Pharmacy, School of Pharmacy, International Campus - Iran University of Medical Sciences 2021 06 19 2021 06 20 The rational use of medicines was and still is a global health priority. In light of the COVID-19 Pandemic, ensuring and practicing the RUM has become even more challenging. Certain interventions from the list of core polciies recommended by the World Health Organization (WHO) bear additional importance in imporving RUM principles in practice. These recommendations are visited in this editorial.  https://jpc.tums.ac.ir/index.php/jpc/article/view/430