Adverse Drug Reactions: Knowledge, Attitude and Practice of Pharmacy
Background: Adverse Drug Reactions (ADRs) are one of the leading causes of morbidity and mortality and contribute to excessive health care costs. Detection and reporting of ADRs could decrease these consequences. The present study was designed to assess the Knowledge, Attitude and Practice (KAP) of pharmacy students towards ADRs monitoring and reporting.
Methods: A questionnaire was prepared to investigate the Knowledge, Attitude and Practice (KAP) of pharmacy students regarding ADR reporting. The questionnaire consisting of 17 questions (7 questions on knowledge, 5 on attitudes and 5 on practice) were given to pharmacy students randomly.
Results: A total of 71 respondents participated in the study. 70% of participants had favorable general knowledge about ADRs but more than 60% of their professional knowledge was not satisfying. 60% of respondent believed that educational intervention will improve participating of health care professional in ADRs reporting. 63% of respondent observed ADRs cases but about 95% of them had never reported an ADR.
Conclusion: In overall, pharmacy students have poor knowledge, attitude and practice towards ADRs reporting and pharmacovigilance. This suggests the need of suitable changes in the undergraduate teaching curriculum and additional training among the students regarding ADRs.
World Health Organization. International drug monitoring: The role of national centres. Report of aWHO meeting. World Health Organ Tech Rep Ser 1972; 498: 1-25.
Baniasadi S, Fahimi F, Shalviri G. Developing an adverse drug reaction reporting system at a teaching hospital. Basic Clin Pharmacol Toxicol 2008; 102(4): 408-11.
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients. JAMA 1998; 279(15): 1200-5.
Moore N, Lecointre D, Noblet C, Mabille M. Frequency and cost of serious adverse drug reactions in a department of general medicine. Br J Clin Pharmacol 1998; 45(3): 301-8.
White TJ, Arakelian A, Rho JP. Counting the costs of drug-related adverse events. Pharmacoeconomics 1999; 15(5): 445-58.
Yadav S. Status of adverse drug reaction monitoring and pharmacovigilance in selected countries. Indian journal of pharmacology 2008; 40(Suppl1): S4.
Green CF, Mottram D, Rowe P, Pirmohamed M. Attitudes and knowledge of hospital pharmacists to adverse drug reaction reporting. Br J Clin Pharmacol 2001; 51(1): 81-6.
Subish P, Mohamed Izham M, Mishra P. Evaluation of the knowledge, attitude and practices on adverse drug reactions and pharmacovigilance among healthcare professionals in a Nepalese hospital- a preliminary study. Internet Journal of Pharmacology 2007; 6(1).
Shalviri G,Valadkhani M, Dinarvand R. Ten years pharmacovigilance activities in Iran. Iran J Public Health 2009; 38(Suppl. 1); 162-6.
Hazell L, Shakir SA. Under-reporting of adverse drug reactions. Drug Saf 2006; 29(5): 385-96.
Moride Y, Haramburu F, Requejo AA, Bégaud B. Under reporting of adverse drug reactions in general practice. Br J Clin Pharmacol 1997; 43(2): 177-181.
Toklu HZ, Uysal MK. The knowledge and attitude of the Turkish community pharmacists toward pharmacovigilance in the Kadikoy district of Istanbul. Pharm World Sci 2008; 30(5): 556-62.
Vessal G, Mardani Z, Mollai M. Knowledge, attitudes, and perceptions of pharmacists to adverse drug reaction reporting in Iran. Pharm World Sci 2009; 31(2): 183-7.
Rehan HS, Vasudev K, Tripathi CD. Adverse drug reaction monitoring: knowledge, attitude and practices of medical students and prescribers. Natl Med J India 2002; 15(1): 24-6.
Ahmad A, Patel I, Balkrishnan R, Mohanta GP, Manna PK. An evaluation of knowledge, attitude and practice of Indian pharmacists towards adverse drug reaction reporting: A pilot study. Perspect Clin Res. 2013;4(4):204-10.
Fadare JO, Enwere O, Afolabi AO, Chedi BAZ, Musa A. Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting among Healthcare Workers in a Tertiary Centre in Northern Nigeria. Trop J Pharm Res 2011; 10 (3): 235-42.
Palaian S, Ibrahim MI, Mishra P. Health professionals’ knowledge, attitude and practices towards pharmacovigilance in Nepal. Pharm Pract (Granada) 2011; 9(4): 228-35.
Palanisamy S, Arul Kumaran K.S.G, Rajasekaran A. A study on assessment of knowledge about adverse drug reactions. Der Pharmacia Lettre 2013. 5 (1): 41-52.
Praveen S, Jai Prakash R, Manjunath GN, Gautham MS, Naveen Kumar. Adverse Drug Reaction reporting among medical and dental practitioners: a KAP study. Indian Journal of Medical Specialities 2013; 4(1): 10-15.
Inman W. Attitudes to adverse drug reaction reporting. Br J Clin Pharmacol 1996; 41(5): 434.
Rajesh R, Vidyasagar S, Muralidhar Varma D. An Educational Interventionto assess Knowledge Attitude Practice of pharmacovigilance among Health care professionals in an Indian tertiary care teaching hospital. Int J PharmTech 2011; 3(2): 678-92.