The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran

  • Saeed Mehralinejadian
  • Mandana Izadpanah Assistant Professor of Clinical Pharmacy, Department of Clinical Pharmacy, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran http://orcid.org/0000-0002-1785-4665
  • Farhad Soltani
  • Sepideh Sayadi
  • Maryam Aghakouchakzadeh
Keywords:
Resistance, ventilator-associated pneumonia, Intensive care Units, Gram-negative microorganisms

Abstract

Increasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pneumonia were included in the study. The prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures.

Based on the results of the study, From 373 hospitalized patients, 38 (10.2%) were diagnosed with VAP. From the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which Enterobacter with 36 cases (39.5%) and E.Coli with 28 cases (30.7%) was most frequently compared to other organisms. Of the 90 organisms responsible for the infection, 43 cases (47.2%) were MDR microorganisms and 47 (51.6%) were XDR microorganisms. Enterobacter and E.Coli were the most prevalent MDR microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. Also, these two microorganisms were the most abundant XDR microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively.

The results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units.

Published
2020-06-26
How to Cite
1.
Mehralinejadian S, Izadpanah M, Soltani F, Sayadi S, Aghakouchakzadeh M. The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran. J Pharm Care. 8(2):83-87.
Section
Brief Report