Letter to the Editor

Voriconazole Film-Coated Tablets: To Split Them or Not?

Abstract

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1. Mangal N, Hamadeh IS, Arwood MJ, et al. Optimization of voriconazole therapy for the treatment of invasive fungal infections in adults. Clin Pharmacol Ther 2018;104(5):957-65.
2. Vfend (Voriconazole) Tablets, Oral Suspension, and IV [package insert]. New York: Pfizier, 2011.
3. Purkins L, Wood N, Ghahramani P, Greenhalgh K, Allen MJ, Kleinermans D. Pharmacokinetics and safety of voriconazole following intravenous- to oral-dose escalation regimens. Antimicrob Agents Chemother 2002;46(8):2546-53.
4. Eldar D. Design, formulation and manufacture of film-coated drug products [2017]. Available from: https://www.europeanpharmaceuticalreview.com/article/68115/design-formulation-manufacture/.
5. Dodds Ashley ES, Zaas AK, Fang AF, Damle B, Perfect JR. Comparative pharmacokinetics of voriconazole administered orally as either crushed or whole tablets. Antimicrob Agents Chemother 2007;51(3):877-80.
6. Practice Ifsm. oral dosage forms that should not be crushed [2020 [Available from: https://www.ismp.org/recommendations/do-not-crush.
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IssueVol 8, No 3 (Summer 2020) QRcode
SectionLetter to the Editor
DOI https://doi.org/10.18502/jpc.v8i3.4551
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How to Cite
1.
Sahraei Z, Barati S. Voriconazole Film-Coated Tablets: To Split Them or Not?. J Pharm Care. 2020;8(3):148-149.