Nonprescription Corticosteroid Use, Per Capita Consumption and Pattern of Distribution of Commonly Used Corticosteroids in Khuzestan Province Pharmacies Throughout 2016
Background: Corticosteroids are widely used in many medical problems; therefore, they are easily available in all types of pharmacies. Because of their dramatic response and different available formulations, the non-prescription use of these drugs is high, even though there are many side effects related to their use. The present study evaluates and compares the data reported by FDA, main health insurance organizations and pharmaceutical companies that distribute the corticosteroids.
Methods: This descriptive correlational, cross-sectional study was designed to assess the prevalence, distribution pattern, per capita prescription and non-prescription consumption of 11 high-consumption corticosteroids in private and public pharmacies of Khuzestan province throughout 2016.
Results: The results indicated that the highest distribution of corticosteroids is related to private pharmacies. Among the cities of Khuzestan, the highest rate of non-prescription use of corticosteroids was in Haftkel city, and the lowest was in Andika city. Among the drugs, prednisolone 5 mg tablets and dexamethasone 5 mg tablets have the highest per capita prescription and non-prescription consumption in Khuzestan province, respectively.
Conclusion: According to the results of this study, the per capita consumption of corticosteroids is high, and the pharmacies seem to dispense these drugs widely. Therefore accurate recording of the distribution and dispense of corticosteroids by FDA on a monthly and annual basis is crucial. It is necessary to increase the supervision of drug companies that provide the supply of corticosteroids.
2. Chuc NT, Tomson G. "Doi moi" and private pharmacies: a case study on dispensing and financial issues in Hanoi, Vietnam. Eur J Clin Pharmacol 1999;55(4):325-32.
3. Ershadpour R, Zare Marzouni H, Kalani N. Review survey of the reasons of the prevalence of self-medication among the people of Iran. Navid 2015;18(60):16-23.
4. Nieman LK. Pharmacologic use of glucocorticoids. In: :André Lacroix Kathryn A Martin, editors. UpTo-Date. [Internet]. Waltham (MA): UpToDate Inc; 2020. [updated 2019 Mar 02; cited 2020 may 14]. Available from: https://www.uptodate.com/contents/pharmacologic-use-of-glucocorticoids
5. Hasselgren PO, Alamdari N, Aversa Z, Gonnella P, Smith IJ, Tizio S. Corticosteroids and muscle wasting: role of transcription factors, nuclear cofactors, and hyperacetylation. Curr Opin Clin Nutr Metab Care 2010;13(4):423-8.
6. Carpenter WT Jr, Gruen PH. Cortisol's effects on human mental functioning. J Clin Psychopharmacol 1982;2(2):91-101.
7. oogood JH, Markov AE, Baskerville J, Dyson C. Association of ocular cataracts with inhaled and oral steroid therapy during long-term treatment of asthma. J Allergy Clin Immunol 1993;91(2):571-9.
8. Donihi AC, Raval D, Saul M, Korytkowski MT, DeVita MA. Prevalence and predictors of corticosteroid-related hyperglycemia in hospitalized patients. Endocr Pract 2006;12(4):358-62.
9. R. Zareshahi, A.a. Haghdoost, A. Asadipour, B. Sadeghirad. Rational usage of drug indices in the prescriptions of kerman medical practitioners in 2008. Journal of Rafsanjan University of Medical Sciences 2012;11(6):523-536.
10. Teymourzadeh E, Babashahy S, Hoseini Shokouhi SM, et al. Hakim Research Journal 2013;16(2):169-170.
11. Ferraz MB, Pereira RB, Paiva JG, Atra E, Dos Santos JQ. Availability of over-the-counter drugs for arthritis in Sao Paulo, Brazil. Soc Sci Med 1996;42(8):1129-31.
12. Rogers J, Wood SM, Garrette EL, et al. Use of nonprescription topical steroids: patients' experiences. Br J Dermatol 2005;152(6):1193-8.
13. Toklu HZ, Akici A, Oktay Ş, Cali S, Sezen SF, Keyer-Uysal M. The pharmacy practice of community pharmacists in Turkey. Marmara Pharmaceutical Journal 2010;14(1):53-60.
14. Laing R, Hogerzeil H, Ross-Degnan D. Ten recommendations to improve use of medicines in developing countries. Health Policy Plan 2001;16(1):13-20.
15. Sinha A, Kar S, Yadav N, Madke B. Prevalence of Topical Steroid Misuse Among Rural Masses. Indian J Dermatol 2016;61(1):119.
16. Moayeri A, Moayeri A. Assessing related factors on the illicit use of medications in Abbas Abad City (Mazandaran): A cross sectional study. Journal of Ilam University of Medical Sciences 2014;22(5):11-19.
17. Chalker J, Ratanawijitrasin S, Chuc NT, Petzold M, Tomson G. Effectiveness of a multi-component intervention on dispensing practices at private pharmacies in Vietnam and Thailand- A randomized controlled trial. Soc Sci Med 2005;60(1):131-41.
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