Implementation of Home Medication Review in Patients with Chronic Diseases: A Pilot Study in Indonesia
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Abstract
Background: The high prevalence of chronic diseases such as diabetes mellitus, hypertension, and dyslipidemia is a concern for pharmacists. Pharmacists are expected to participate in these efforts by implementing Home Medication Review (HMR). HMR is a community-based collaborative service outside of health facilities that involves physicians and pharmacists to improve the effectiveness of therapy. This study aimed to determine the incidence of drug-related problems (DRPs), the level of patient satisfaction, and the effect of improving the quality of life of patients with chronic diseases who received Home Medication Review services at the Banjarbaru Utara Primary Health Care.
Methods: This study used a quasi-experimental method with a single group pre-test and post-test design. Data were obtained prospectively, from January to May 2024. DRPs were measured by the Pharmaceutical Care Network Europe (PCNE) form. Patient satisfaction was measured using the five-dimensional service quality questionnaire. Quality of life was measured using the EQ-5D-5L questionnaire with the EQ-5D-5L Index and EQ Visual Analog Scale (VAS) parameters.
Results: The study showed that DRPs in patients with chronic diseases before undergoing HMR were 92.50%. Patient satisfaction with HMR services reached 91.33%. Quality of life in chronic disease patients increased, based on the EQ-5D-5L Index, from 0.802 + 0.199 before to 0.854 + 0.189 after HMR (p-value 0.002), and based on the EQ VAS from 72.25 + 12.80 before to 78.12 + 14.19 after HMR (p-value 0.001).
Conclusion: This study concludes that HMR services can identify DRPs, and improve satisfaction, knowledge, and quality of life of patients with chronic disease.
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17. Rosli MR, Neoh CF, Wu DB, et al. Home medication review for patients with type 2 diabetes mellitus by community pharmacists: a randomised controlled trial. Pharm Pract. 2021;19(3):2397.
18. Temkin SM, Barr E, Moore H, Caviston JP, Regensteiner JG, Clayton JA. Chronic conditions in women: the development of a national institutes of health framework. BMC Women’s Health. 2023;23(1):162.
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22. Holman HR. The relation of the chronic disease epidemic to the health care crisis. ACR Open Rheumatol. 2020;2(3):167–73.
23. Liou WS, Huang SM, Lee WH, Chang YL, Wu MF. The effects of a pharmacist-led medication review in a nursing home: a randomized controlled trial. Medicine. 2021;100(48):e28023.
24. Basheti IA, Qunaibi EA, AbuRuz S, Samara S, Bulatova NR. Home Medication Reviews in a Patient Care Experience for Undergraduate Pharmacy Students. Am J Pharm Educ. 2013;77(8):173.
25. Arini YD, Rahmawati F, Andayani TM. Faktor risiko kejadian drug related problems pada pasien penyakit kronis rawat jalan di poliklinik penyakit dalam. Jurnal Manajemen dan Pelayanan Farmasi. 2016;6(2):83–94.
26. Lee CY, Beanland C, Goeman D, et al. Improving medication safety for home nursing clients: a prospective observational study of a novel clinical pharmacy service-the visiting pharmacist (VIP) study. J Clin Pharm Ther. 2018;43(6):813–21.
27. Martins RR, Farias AD, Oliveira YMDC, Diniz RDS, Oliveira AG. Prevalence and risk factors of inadequate medicine home storage: a community-based study. Rev saude publica. 2017;51(95):1–8.
28. Cheng M, Ren L, Jia X, Wang J, Cong B. Understanding the action mechanisms of metformin in the gastrointestinal tract. Front Pharmacol. 2024;15:1347047.
29. Lorato GS, Perumal-Pillay VA, Suleman F. Assessment of community pharmacists’ knowledge and perception of pharmaceutical care in South Africa: a cross-sectional survey. Journal of Pharmaceutical Care. 2024;12(2):66–72.
30. Sawan M, O’Donnell LK, Reeve E, et al. The utility of a computerized clinical decision support system intervention in home medicines review: a mixed-methods process evaluation. Research in Social and Administrative Pharmacy. 2021;17(4):715–22.
31. Purwonugroho TA, Raharjo B, Maharani L, et al. Community pharmacist home visit-based intervention improved diabetes patients’ outcomes: a randomized controlled trial. Journal of Applied Pharmaceutical Science. 2021;11(3):54–9.
2. Kementerian Kesehatan. Laporan Nasional Riskesdas 2018. Jakarta: Kementerian Kesehatan RI; 2019. Available from: URL: https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/1/Laporan%20Riskesdas%202018%20Nasional.pdf
3. World Health Organization. Noncommunicable Diseases. 2023. Available from: https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases
4. Park S, Nam JY. Effects of changes in multiple chronic conditions on medical costs among older adults in South Korea. Healthcare. 2022;10(4):742.
5. Skinner H, Coffey R, Jones J, Heslin K, Moy E. The effects of multiple chronic conditions on hospitalization costs and utilization for ambulatory care sensitive conditions in the United States: a nationally representative cross-sectional study. BMC Health Services Research. 2016;16:77.
6. Coleman J, Pontefract S. Adverse Drug Reactions. Clinical Medicine. 2016;16(5):481–5.
7. Ali S, Mishra A, Palaksha S, Adepu R, Nataraj B, Kumar B. Home medicine review (HMR) service. The International Journal of Therapeutics. 2018;1(1):8–20.
8. Pharmaceutical Society of Australia. Guidelines for pharmacists providing Home Medicines Review (HMR) services. Pharmaceutical Society of Australia; 2011. Available from: URL: https://www.ppaonline.com.au/wp-content/uploads/2019/01/PSA-Guidelines-for-Providing-Home-Medicines-Review-HMR-Services.pdf
9. Kementerian Kesehatan. Pedoman Pelayanan Kefarmasian Di Rumah (Home Pharmacy Care). Jakarta: Kementerian Kesehatan RI; 2020. Available from: URL: http://repo.upertis.ac.id/1910/1/Pedoman%20Home%20Pharmacy%20Care.pdf
10. Pharmaceutical Care Network Europe Association. PCNE Classification for drug-related problems V9. 1. vol. 2020;1:22-8.
11. Hamida N, Ulfa M, Haris R, Endarti D, Wiedyaningsih C. pengukuran kualitas hidup pasien program pengelolaan penyakit kronis (prolanis) di puskesmas menggunakan instrumen EQ-5D-5L. Majalah Farmaseutik. 2019;15(2):67–73.
12. Susanto H. Kualitas pelayanan puskesmas asembagus dan kepuasan pasien di kecamatan asembagus kabupaten situbondo. ACTON : Jurnal Ilmiah. 2023;19(1):17–29.
13. Sluggett JK, Collier LR, Bartholomaeus JD, Inacio MC, Wesselingh SL, Caughey GE. National trends and policy impacts on provision of home medicines reviews and residential medication management reviews in older Australians, 2009–2019. Int J Environ Res Public Health. 2021;18(18):9898.
14. Du W, Gnjidic D, Pearson SA, et al. Patterns of high-risk prescribing and other factors in relation to receipt of a home medicines review: a prospective cohort investigation among adults aged 45 years and over in Australia. BMJ Open. 2019;9(2):e027305.
15. Rashmi R, Mohanty SK. Examining Chronic Disease Onset Across Varying Age Groups Of Indian Adults Using Competing Risk Analysis. Sci Rep. 2023;13(1):5848.
16. Sari OM, Putra AMP. Severity and risk rating of drug-drug interaction potency in chronic kidney disease in public health hospital. Journal of Pharmaceutical Care. 2024;12(2):78–87.
17. Rosli MR, Neoh CF, Wu DB, et al. Home medication review for patients with type 2 diabetes mellitus by community pharmacists: a randomised controlled trial. Pharm Pract. 2021;19(3):2397.
18. Temkin SM, Barr E, Moore H, Caviston JP, Regensteiner JG, Clayton JA. Chronic conditions in women: the development of a national institutes of health framework. BMC Women’s Health. 2023;23(1):162.
19. Xiang D, Liu Y, Zhou S, Zhou E, Wang Y. Protective effects of estrogen on cardiovascular disease mediated by oxidative stress. Oxid Med Cell Longev. 2021:5523516.
20. BPS Kalsel. Angka Partisipasi Murni Sekolah Menengah Atas (SMA). In Banjarmasin: Badan Pusat Statistik Provinsi Kalimantan Selatan; 2022. Available from: URL: https://banjarbarukota.bps.go.id/id/statistics-table/2/OTIjMg==/angka-partisipasi-murni-apm-sma-sederajat.html
21. Zafasia AF, Deli H, Arneliwati A. Hubungan jarak rumah dan waktu tempuh dengan pemanfaatan pelayanan kesehatan selama pandemi. Journal Oline Mahsiswa (JOM) FKp. 2022;9(2):161–8.
22. Holman HR. The relation of the chronic disease epidemic to the health care crisis. ACR Open Rheumatol. 2020;2(3):167–73.
23. Liou WS, Huang SM, Lee WH, Chang YL, Wu MF. The effects of a pharmacist-led medication review in a nursing home: a randomized controlled trial. Medicine. 2021;100(48):e28023.
24. Basheti IA, Qunaibi EA, AbuRuz S, Samara S, Bulatova NR. Home Medication Reviews in a Patient Care Experience for Undergraduate Pharmacy Students. Am J Pharm Educ. 2013;77(8):173.
25. Arini YD, Rahmawati F, Andayani TM. Faktor risiko kejadian drug related problems pada pasien penyakit kronis rawat jalan di poliklinik penyakit dalam. Jurnal Manajemen dan Pelayanan Farmasi. 2016;6(2):83–94.
26. Lee CY, Beanland C, Goeman D, et al. Improving medication safety for home nursing clients: a prospective observational study of a novel clinical pharmacy service-the visiting pharmacist (VIP) study. J Clin Pharm Ther. 2018;43(6):813–21.
27. Martins RR, Farias AD, Oliveira YMDC, Diniz RDS, Oliveira AG. Prevalence and risk factors of inadequate medicine home storage: a community-based study. Rev saude publica. 2017;51(95):1–8.
28. Cheng M, Ren L, Jia X, Wang J, Cong B. Understanding the action mechanisms of metformin in the gastrointestinal tract. Front Pharmacol. 2024;15:1347047.
29. Lorato GS, Perumal-Pillay VA, Suleman F. Assessment of community pharmacists’ knowledge and perception of pharmaceutical care in South Africa: a cross-sectional survey. Journal of Pharmaceutical Care. 2024;12(2):66–72.
30. Sawan M, O’Donnell LK, Reeve E, et al. The utility of a computerized clinical decision support system intervention in home medicines review: a mixed-methods process evaluation. Research in Social and Administrative Pharmacy. 2021;17(4):715–22.
31. Purwonugroho TA, Raharjo B, Maharani L, et al. Community pharmacist home visit-based intervention improved diabetes patients’ outcomes: a randomized controlled trial. Journal of Applied Pharmaceutical Science. 2021;11(3):54–9.
| Files | ||
| Issue | Vol 12, No 4 (Autumn 2024) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/jpc.v12i4.17452 | |
| Keywords | ||
| Chronic Diseases Drug-Related Problems Home Medication Review Pharmacist | ||
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How to Cite
1.
Silviana M, Ningrum V, Mafruhah O. Implementation of Home Medication Review in Patients with Chronic Diseases: A Pilot Study in Indonesia. J Pharm Care. 2024;12(4):213-220.
